SCHEMBL29762008

SCHEMBL29762008

O=[13C](O)c1ccc2c(c1)sc1ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.54
GPR3 P46089 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
RAB9A P51151 2/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
KDM4E B2RXH2 3/20 0.49
LMNA P02545 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
MCL1 Q07820 1/20 0.47
TTR P02766 3/20 0.46
PARP1 P09874 1/20 0.46
PTPN7 P35236 1/20 0.44
DUSP3 P51452 1/20 0.44
PTPN12 Q05209 1/20 0.44
PTPN22 Q9Y2R2 1/20 0.44
PMM2 O15305 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11249253 1.00 CYP1A2 (0.54) CYP1A2GPR3SMN1; SMN2RAB9AALDH1A1
SCHEMBL11244432 0.98 CYP1A2 (0.53) CYP1A2GPR3SMN1; SMN2RAB9AALDH1A1
SCHEMBL490172 0.91 TTR (0.54) CYP1A2SMN1; SMN2RAB9AALDH1A1MAPT
SCHEMBL30414903 0.90 KDM4E (0.48) CYP1A2SMN1; SMN2RAB9AALDH1A1MAPT
SCHEMBL204515 0.90 KDM4E (0.48) CYP1A2SMN1; SMN2RAB9AALDH1A1MAPT
SCHEMBL30839928 0.89 CYP1A2 (0.67) CYP1A2GPR3SMN1; SMN2RAB9AALDH1A1
SCHEMBL3111619 0.89 CYP1A2 (0.67) CYP1A2GPR3SMN1; SMN2RAB9AALDH1A1
SCHEMBL15041003 0.87 GPR3 (0.54) CYP1A2GPR3SMN1; SMN2RAB9AALDH1A1
SCHEMBL15041034 0.87 GPR3 (0.54) CYP1A2GPR3SMN1; SMN2RAB9AALDH1A1
SCHEMBL30414825 0.86 KDM4E (0.46) CYP1A2SMN1; SMN2RAB9AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114933511-B Method for quickly converting carboxyl into aldehyde group 中国科学院兰州化学物理研究所 2023-02-24 CN disclosed
CN-114933511-A Method for quickly converting carboxyl into aldehyde group 中国科学院兰州化学物理研究所 2022-08-23 CN disclosed