SCHEMBL2976308

SCHEMBL2976308

Cc1cc(C)c(C2=CCc3cc(Br)ccc32)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
RAPGEF4 Q8WZA2 2/20 0.34
CYP3A4 P08684 2/20 0.33
METAP1 P53582 2/20 0.33
PGR P06401 2/20 0.32
TDP2 O95551 1/20 0.32
PARP10 Q53GL7 1/20 0.32
PARP11 Q9NR21 1/20 0.32
SRD5A1 P18405 2/20 0.31
SRD5A2 P31213 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2975148 0.87 MEN1 (0.47) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2963487 0.73 METAP1 (0.39) ALDH1A1METAP1PGRTDP2PARP10
SCHEMBL2963361 0.73 CYP3A4 (0.42) ALDH1A1CYP3A4METAP1TDP2PARP10
SCHEMBL2965054 0.72 MAPT (0.39) ALDH1A1MAPTSMN1; SMN2CYP3A4METAP1
SCHEMBL2970943 0.72 NPC1 (0.37) MEN1ALDH1A1MAPTKMT2ACYP3A4
SCHEMBL2965972 0.71 METAP1 (0.39) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2962748 0.71 ALDH1A1 (0.47) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2966449 0.70 ALDH1A1 (0.39) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2963510 0.69 MEN1 (0.41) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2967877 0.68 MEN1 (0.40) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 MEN1 750/4885ALDH1A1 4332/4885MAPT 206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.