Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOA | P61586 | 1/20 | 0.56 |
| ▸ | IDH1 | O75874 | 10/20 | 0.50 |
| ▸ | IDH2 | P48735 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15094676 | 1.00 | RHOA (0.56) | RHOAIDH1IDH2POLBNPC1 | |
| SCHEMBL15094853 | 0.89 | KCNH3 (0.49) | IDH1IDH2POLBNPC1RAB9A | |
| SCHEMBL29561107 | 0.87 | IDH1 (0.51) | RHOAIDH1IDH2POLBNPC1 | |
| SCHEMBL15094875 | 0.87 | IDH1 (0.51) | RHOAIDH1IDH2POLBNPC1 | |
| SCHEMBL29560995 | 0.86 | KCNH3 (0.66) | IDH1IDH2POLBKCNH3 | |
| SCHEMBL15102366 | 0.86 | KCNH3 (0.66) | IDH1IDH2POLBKCNH3 | |
| SCHEMBL20018006 | 0.84 | POLB (0.71) | IDH1IDH2POLBKCNH3 | |
| SCHEMBL15102285 | 0.82 | IDH1 (0.53) | IDH1IDH2POLBKCNH3 | |
| SCHEMBL29561084 | 0.82 | IDH1 (0.53) | IDH1IDH2POLBKCNH3 | |
| SCHEMBL15102422 | 0.81 | IDH1 (0.62) | IDH1IDH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536635-A | Therapeutically active compounds and methods of use thereof | 法国施维雅药厂 | 2022-12-30 | — | — | CN | disclosed |
| CN-115521264-A | Therapeutically active compounds and methods of use thereof | 法国施维雅药厂 | 2022-12-27 | — | — | CN | disclosed |
| CN-114933585-A | Therapeutically active compounds and methods of use thereof | 法国施维雅药厂 | 2022-08-23 | — | — | CN | disclosed |
| CN-108912066-B | Therapeutically active compounds and methods of use thereof | 安吉奥斯医药品有限公司 | 2022-06-24 | — | — | CN | disclosed |