Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15102521 | 1.00 | IDH2 (0.49) | IDH2ALDH1A1LMNAKDM4ECSNK2A2 | |
| SCHEMBL27987836 | 0.88 | IDH2 (0.47) | IDH2ALDH1A1LMNAHPGDKCNH3 | |
| SCHEMBL15102519 | 0.86 | LMNA (0.54) | IDH2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL16392087 | 0.85 | MEN1 (0.52) | ALDH1A1LMNAKDM4ECSNK2A2CSNK2A1 | |
| SCHEMBL15102348 | 0.84 | IDH2 (0.52) | IDH2ALDH1A1LMNAHPGDKCNH3 | |
| SCHEMBL15102561 | 0.83 | IDH2 (0.55) | IDH2ALDH1A1LMNAHPGDRHOA | |
| SCHEMBL15102371 | 0.80 | PTGIR (0.52) | IDH2ALDH1A1RHOASMN1; SMN2MAOB | |
| SCHEMBL15102360 | 0.80 | ADORA1 (0.59) | IDH2ALDH1A1LMNAHPGDKCNH3 | |
| SCHEMBL15094826 | 0.79 | IDH2 (0.59) | IDH2ALDH1A1LMNARHOARORC | |
| SCHEMBL15102281 | 0.79 | IDH2 (0.55) | IDH2ALDH1A1LMNAKDM4EKCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536635-A | Therapeutically active compounds and methods of use thereof | 法国施维雅药厂 | 2022-12-30 | — | — | CN | disclosed |
| CN-115521264-A | Therapeutically active compounds and methods of use thereof | 法国施维雅药厂 | 2022-12-27 | — | — | CN | disclosed |
| CN-114933585-A | Therapeutically active compounds and methods of use thereof | 法国施维雅药厂 | 2022-08-23 | — | — | CN | disclosed |
| CN-108912066-B | Therapeutically active compounds and methods of use thereof | 安吉奥斯医药品有限公司 | 2022-06-24 | — | — | CN | disclosed |