Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 10/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 8/20 | 0.47 |
| ▸ | JAK2 | O60674 | 7/20 | 0.47 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29768175 | 0.91 | IRAK4 (0.50) | IRAK4NTRK1JAK2SMPD3 | |
| SCHEMBL29768038 | 0.91 | IRAK4 (0.50) | IRAK4NTRK1JAK2SMPD3 | |
| SCHEMBL21997557 | 0.90 | IRAK4 (0.47) | IRAK4SMPD3 | |
| SCHEMBL26765556 | 0.88 | IRAK4 (0.46) | IRAK4SMPD3 | |
| SCHEMBL30267223 | 0.86 | NTRK1 (0.47) | IRAK4NTRK1JAK2SMPD3 | |
| SCHEMBL21997350 | 0.82 | TGFBR1 (0.44) | IRAK4SMPD3 | |
| SCHEMBL29692535 | 0.81 | SMPD3 (0.66) | IRAK4NTRK1JAK2SMPD3 | |
| SCHEMBL25339224 | 0.81 | IRAK4 (0.51) | IRAK4SMPD3 | |
| Hydrochloric Acid SCHEMBL30460079 | 0.81 | SMPD3 (0.64) | IRAK4NTRK1JAK2SMPD3 | |
| SCHEMBL19560063 | 0.80 | SMPD3 (0.63) | IRAK4NTRK1JAK2SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613748-A1 | IRAK4 DEGRADATION AGENT AND USE THEREOF | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-116648248-B | Aromatic compound, pharmaceutical composition containing same and application thereof | 成都茵创园医药科技有限公司 | 2025-04-15 | — | — | CN | disclosed |
| EP-4393922-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| CN-116648248-A | Aromatic compound, pharmaceutical composition containing same and application thereof | 成都茵创园医药科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| WO-2022161414-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND APPLICATION THEREOF | 成都茵创园医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |