Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.56 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1929302 | 0.87 | CHRNB4 (0.66) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL1928695 | 0.82 | CHRNB4 (0.72) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL1928412 | 0.82 | CHRNB4 (0.72) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL14578209 | 0.78 | CHRNB4 (0.74) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL23167244 | 0.77 | HRH3 (0.45) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL29772014 | 0.77 | HRH3 (0.45) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL23178053 | 0.77 | HRH3 (0.45) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL10881783 | 0.77 | CHRNB4 (0.68) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL11448897 | 0.74 | CHRNB4 (0.52) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL10874140 | 0.73 | CHRNB4 (0.64) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761085-A | Compounds useful as immunomodulators | 百时美施贵宝公司 | 2022-07-15 | — | — | CN | disclosed |