Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12006635 | 0.78 | MAPT (0.46) | MAPTSIRT6PPARGALDH1A1LMNA | |
| SCHEMBL12006634 | 0.78 | MAPT (0.46) | MAPTSIRT6PPARGALDH1A1LMNA | |
| SCHEMBL791700 | 0.78 | MAPT (0.46) | MAPTSIRT6PPARGALDH1A1LMNA | |
| SCHEMBL6714741 | 0.77 | ALDH1A1 (0.53) | MAPTSIRT6ALDH1A1LMNAPOLB | |
| SCHEMBL3136982 | 0.77 | CUL4A (0.51) | MAPTADRB1SIRT6ALDH1A1LMNA | |
| SCHEMBL28185991 | 0.76 | MAPT (0.47) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL3244415 | 0.74 | MAPT (0.44) | MAPTPPARGALDH1A1LMNAPOLB | |
| SCHEMBL2886399 | 0.74 | MAPT (0.49) | MAPTALDH1A1LMNASIGMAR1HRH3 | |
| SCHEMBL12006068 | 0.74 | MAPT (0.49) | MAPTALDH1A1LMNASIGMAR1HRH3 | |
| SCHEMBL3125630 | 0.74 | FFAR1 (0.46) | MAPTPPARGALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853846-A | Androgen receptor degradation agent and application thereof | 苏州国匡医药科技有限公司 | 2022-08-05 | — | — | CN | disclosed |