Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 15/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 13/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772287 | 0.90 | PRMT5 (0.44) | PRMT5METTL3 | |
| SCHEMBL25015483 | 0.90 | PRMT5 (0.44) | PRMT5METTL3 | |
| SCHEMBL29772257 | 0.84 | CYP1A2 (0.37) | PRMT5METTL3ADORA3 | |
| SCHEMBL23273885 | 0.84 | CYP1A2 (0.37) | PRMT5METTL3ADORA3 | |
| SCHEMBL29611113 | 0.80 | HTR2B (0.41) | PRMT5METTL3ADORA3 | |
| SCHEMBL24313826 | 0.80 | HTR2B (0.41) | PRMT5METTL3ADORA3 | |
| SCHEMBL27090421 | 0.80 | HTR2B (0.41) | PRMT5METTL3ADORA3 | |
| SCHEMBL30106843 | 0.79 | CYP1A2 (0.36) | PRMT5METTL3ADORA3 | |
| SCHEMBL23273740 | 0.78 | PRMT5 (0.57) | PRMT5METTL3 | |
| SCHEMBL29772267 | 0.78 | PRMT5 (0.57) | PRMT5METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4048674-A2 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2022-08-31 | — | — | EP | disclosed |
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |