Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 5/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 4/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313826 | 1.00 | HTR2B (0.41) | HTR2BSIGMAR1HTR1DTMEM97ADORA3 | |
| SCHEMBL27090421 | 1.00 | HTR2B (0.41) | HTR2BSIGMAR1HTR1DTMEM97ADORA3 | |
| SCHEMBL29772257 | 0.88 | CYP1A2 (0.37) | ADORA3PRMT5METTL3ALDH1A1CYP1A2 | |
| SCHEMBL30106843 | 0.88 | CYP1A2 (0.36) | ADORA3PRMT5METTL3ALDH1A1CYP1A2 | |
| SCHEMBL23273885 | 0.88 | CYP1A2 (0.37) | ADORA3PRMT5METTL3ALDH1A1CYP1A2 | |
| SCHEMBL29611607 | 0.84 | ADORA1 (0.54) | HTR2BSIGMAR1HTR1DTMEM97ADORA3 | |
| SCHEMBL27090409 | 0.84 | ADORA1 (0.54) | HTR2BSIGMAR1HTR1DTMEM97ADORA3 | |
| SCHEMBL23273892 | 0.81 | ADORA3 (0.44) | HTR2BSIGMAR1HTR1DTMEM97ADORA3 | |
| SCHEMBL29772259 | 0.80 | PRMT5 (0.39) | ADORA3PRMT5METTL3 | |
| SCHEMBL23313210 | 0.79 | HTR2B (0.51) | HTR2BSIGMAR1HTR1DTMEM97ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229067-A1 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |