Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 15/20 | 0.98 |
| ▸ | PRMT5 | O14744 | 15/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273845 | 1.00 | METTL3 (0.98) | METTL3PRMT5 | |
| SCHEMBL25015662 | 1.00 | METTL3 (0.98) | METTL3PRMT5 | |
| SCHEMBL23313940 | 0.99 | METTL3 (1.00) | METTL3PRMT5 | |
| SCHEMBL23313197 | 0.95 | PRMT5 (1.00) | METTL3PRMT5 | |
| SCHEMBL23313943 | 0.93 | METTL3 (0.86) | METTL3PRMT5 | |
| SCHEMBL23313226 | 0.92 | PRMT5 (1.00) | METTL3PRMT5 | |
| SCHEMBL25016870 | 0.92 | PRMT5 (1.00) | METTL3PRMT5 | |
| SCHEMBL23313100 | 0.90 | METTL3 (1.00) | METTL3PRMT5 | |
| SCHEMBL23273743 | 0.89 | METTL3 (1.00) | METTL3PRMT5 | |
| SCHEMBL23313257 | 0.89 | METTL3 (1.00) | METTL3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4048674-A2 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2022-08-31 | — | — | EP | disclosed |
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |