Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772742 | 0.82 | PTGDR2 (0.39) | PTGDR2TP53KDM4EALDH1A1HTT | |
| SCHEMBL29772766 | 0.80 | NPC1 (0.37) | PTGDR2TP53KDM4EALDH1A1HTT | |
| SCHEMBL1748604 | 0.78 | PTGDR2 (0.39) | PTGDR2KDM4EALDH1A1HTTNPSR1 | |
| SCHEMBL21490844 | 0.78 | PTGDR2 (0.46) | PTGDR2KDM4EALDH1A1HTTNPSR1 | |
| SCHEMBL1777928 | 0.78 | MAPT (0.48) | PTGDR2TP53KDM4EHTTLMNA | |
| SCHEMBL16546220 | 0.77 | PTGS2 (0.46) | PTGDR2ALDH1A1 | |
| SCHEMBL30726581 | 0.76 | PTGDR2 (0.39) | PTGDR2KDM4EALDH1A1HTTNPSR1 | |
| SCHEMBL2991481 | 0.76 | PTGDR2 (0.38) | PTGDR2KDM4EALDH1A1HTTNPSR1 | |
| SCHEMBL29772816 | 0.75 | PTGDR2 (0.35) | PTGDR2KDM4EALDH1A1HTTNPSR1 | |
| SCHEMBL1748718 | 0.75 | PTGDR2 (0.39) | PTGDR2TP53KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098763-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| EP-4274832-A1 | TYK2 INHIBITORS | Biogen MA Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150446-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2022-07-14 | — | — | WO | disclosed |