Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949143 | 1.00 | HTR2A (0.50) | HTR2AHTR2CSLC6A2SLC6A4OXER1 | |
| SCHEMBL28979 | 0.81 | HTR2A (0.49) | HTR2AHTR2CSLC6A2SLC6A4MAPT | |
| SCHEMBL850727 | 0.79 | HTR2C (0.50) | HTR2AHTR2CSLC6A2SLC6A4CYP19A1 | |
| SCHEMBL413823 | 0.79 | HTR2A (0.50) | HTR2AHTR2CSLC6A2SLC6A4CYP19A1 | |
| SCHEMBL2073701 | 0.79 | PRKCI (0.53) | HTR2AHTR2CMAPTKDM4E | |
| SCHEMBL2502244 | 0.79 | KDM4E (0.36) | HTR2AHTR2CCYP19A1MAPTKMT2A | |
| SCHEMBL3327014 | 0.79 | MAPT (0.33) | HTR2AHTR2CMAPT | |
| SCHEMBL30967900 | 0.79 | HTR2A (0.50) | HTR2AHTR2CSLC6A2SLC6A4CYP19A1 | |
| SCHEMBL29119 | 0.77 | HTR2C (0.54) | HTR2CSLC6A2SLC6A4MAPTPRMT5 | |
| SCHEMBL7325942 | 0.76 | CA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025760-A1 | PROCESS FOR THE BORYLATION OF ARENES AND HETEROARYLS | THE UNIVERSITY OF MANCHESTER (GB) | 2012-03-01 | — | — | WO | disclosed |