Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL8845344 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL6229893 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL3633829 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL478325 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL17074002 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL6055779 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1065771 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1741351 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL372478 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL2460192 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 47639 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746864-A1 | C5 KETONE COMPOSITIONS AND RELATED METHODS FOR TREATING METABOLIC DYSFUNCTION | Keto Innovations, LLC (US) | 2026-05-27 | — | — | EP | claimed |
| EP-4401569-B1 | BULK MELT-TO-MAKE PECTIN-BASED GUMMY MIX PRECURSOR AND METHODS OF MAKING AND USING | M2M GUMMIES LLC (US) | 2026-05-27 | — | — | EP | claimed |
| CN-122074674-A | Double-modified dietary fiber-based sugar-control health food and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122074633-A | Flavour composition, aqueous food composition containing said flavour composition, preparation and use thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122074667-A | Nanometer oral liquid for sports nutrition, and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075572-A | Composite agent of Tibetan bath composition and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-118930823-B | Multi-component copolyester and preparation method thereof | Guogao high polymer material industry innovation center Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122094704-A | Formulations for oral administration of active agents comprising a combination of acid-neutralizing polymer and non-polymeric material | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075553-A | Composition of metagen and calcium salt and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-121591532-B | Saline-alkali-resistant organic water-soluble fertilizer and preparation method thereof | Jingmen Famax Technology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| US-4167214-A | Process for stably sequestering iron while acidizing a reservoir | SHELL OIL COMPANY (US) | 1979-09-11 | — | — | US | claimed |
| US-4166142-A | PROCESS CHEESE CONTAINING A MODIFIED WHEY SOLIDS | STAUFFER CHEMICAL COMPANY (US) | 1979-08-28 | — | — | US | claimed |
| US-4143168-A | GUM; FOR PET FOODS | THE QUAKER OATS COMPANY (US) | 1979-03-06 | — | — | US | claimed |
| US-4142991-A | TITANIUM TRICHLORIDE | STAUFFER CHEMICAL COMPANY (US) | 1979-03-06 | — | — | US | claimed |
| US-4080477-A | Processed cheese-like product containing soy cheese | FUJI OIL CO., LTD. (JA) | 1978-03-21 | — | — | US | claimed |
| US-4072734-A | ACID OR NEUTRAL SALT OF 1,8-DIAZABICYCLO/5,4,0/UNDECENE-7 | OSAKA SODA CO. LTD. (JA) | 1978-02-07 | — | — | US | claimed |
| US-4029606-A | ACYL-POLYHYDROXY CARBOXYLATE | LION FAT & OIL CO., LTD. (JA) | 1977-06-14 | — | — | US | claimed |
| US-4013784-A | DELAYED RELEASE PHARMACEUTICAL PREPARATIONS | SPEISER PETER | 1977-03-22 | — | — | US | claimed |
| US-3982025-A | Soy cheese spread and process for preparing same | FUJI OIL COMPANY, LTD. (JA) | 1976-09-21 | — | — | US | claimed |
| US-3964255-A | Method of inflating an automobile passenger restraint bag | SPECIALTY PRODUCTS DEVELOPMENT CORPORATION (US) | 1976-06-22 | — | — | US | claimed |