Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 3/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 3/20 | 0.42 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690498 | 1.00 | PTK2 (0.60) | PTK2MAPK10MAPK8PTGS2MAPK3 | |
| SCHEMBL13299170 | 0.89 | PTK2 (0.64) | PTK2MAPK10MAPK8PTGS2MAPK3 | |
| SCHEMBL719807 | 0.88 | PTGS2 (0.50) | PTK2MAPK10MAPK8PTGS2MAPK3 | |
| SCHEMBL12103007 | 0.87 | PTK2 (0.65) | PTK2MAPK10MAPK8PTGS2MAPK3 | |
| SCHEMBL29777593 | 0.86 | MAPK10 (0.65) | PTK2MAPK10MAPK8MAPK3MAPK1 | |
| SCHEMBL690590 | 0.86 | MAPK10 (0.65) | PTK2MAPK10MAPK8MAPK3MAPK1 | |
| SCHEMBL29777580 | 0.84 | PTK2 (0.46) | PTK2MAPK10MAPK8PTGS2MAPK3 | |
| SCHEMBL29777630 | 0.84 | PTK2 (0.46) | PTK2MAPK10MAPK8PTGS2MAPK3 | |
| SCHEMBL689687 | 0.84 | PTGS2 (0.47) | PTK2MAPK10MAPK8PTGS2MAPK3 | |
| SCHEMBL690156 | 0.82 | MAPK8 (0.50) | PTK2MAPK10MAPK8PTGS2MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108948019-B | Focal adhesion kinase inhibitors and uses thereof | 广东东阳光药业有限公司 | 2022-07-08 | — | — | CN | disclosed |