SCHEMBL29778

SCHEMBL29778

N[C@H](Cc1ccc(O)c(Cl)c1)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.73
USP2 O75604 3/20 0.73
PTGS1 P23219 2/20 0.73
KDM4E B2RXH2 2/20 0.73
ALOX15 P16050 2/20 0.73
RECQL P46063 2/20 0.73
HIF1A Q16665 2/20 0.73
HSD17B10 Q99714 2/20 0.73
TDP1 Q9NUW8 2/20 0.73
EGFR P00533 1/20 0.73
LCK P06239 1/20 0.73
FYN P06241 1/20 0.73
ADORA3 P0DMS8 1/20 0.73
HTR2A P28223 1/20 0.73
PTGS2 P35354 1/20 0.73
CA2 P00918 3/20 0.57
PKM P14618 3/20 0.53
ALPI P09923 1/20 0.53
XIAP P98170 1/20 0.53
GRIA2 P42262 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157442 1.00 SLC7A5 (0.73) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL29405778 1.00 SLC7A5 (0.73) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL28512 1.00 SLC7A5 (0.73) SLC7A5USP2PTGS1KDM4EALOX15
Hydrochloric Acid SCHEMBL7042725 0.98 SLC7A5 (0.71) SLC7A5USP2PTGS1KDM4EALOX15
Hydrochloric Acid SCHEMBL7042729 0.98 SLC7A5 (0.71) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL9506322 0.91 SLC7A5 (0.61) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL25578547 0.87 ALOX15 (0.54) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL29478421 0.86 SLC7A5 (0.62) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL43915 0.86 SLC7A5 (0.62) SLC7A5USP2PTGS1KDM4EALOX15
Levodopa SCHEMBL29868926 0.86 SLC7A5 (0.96) SLC7A5USP2PTGS1KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11931329-B2 Compositions and methods for treating anxiety-related disorders YAMO PHARMACEUTICALS LLC (US) 2024-03-19 US claimed
US-20240024268-A1 Methods for Dopamine Modulation in Human Neurologic Diseases SACKNER BERNSTEIN JONATHAN (US) 2024-01-25 US claimed
US-20240016815-A1 COMPOSITIONS AND METHODS FOR MODULATING CANCER IN NON-HUMAN MAMMALS HOFFMAN TECHNOLOGIES LLC 2024-01-18 US claimed
US-11806326-B2 Methods for dopamine modulation in human neurologic diseases SACKNER BERNSTEIN JONATHAN (US) 2023-11-07 US claimed
US-20230331779-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND SHAANXI MICOT TECHNOLOGY CO., LTD. (CN) 2023-10-19 US claimed
US-11786496-B2 Composition and methods for treating intestinal hyperpermeability YAMO PHARMACEUTICALS LLC (US) 2023-10-17 US claimed
EP-4212542-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND Shaanxi Micot Technology Limited Company (CN) 2023-07-19 EP claimed
US-20230141609-A1 Methods of Treating Amyotrophic Lateral Sclerosis and Symptoms YAMO PHARMACEUTICALS LLC (US) 2023-05-11 US claimed
US-20230040681-A1 COMPOSITIONS AND METHODS FOR TREATING ANXIETY-RELATED DISORDERS YAMO PHARMACEUTICALS LLC (US) 2023-02-09 US claimed
US-11534420-B2 Compositions and methods for treating cancer TYME, INC. (US) 2022-12-27 US claimed
WO-2015061328-A2 COMPOSITIONS AND METHODS FOR TREATING INTESTINAL HYPERPERMEABILITY HOFFMAN STEVEN (US) 2015-04-30 WO claimed
WO-2015061288-A1 TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM TYME, INC. (US) 2015-04-30 WO claimed
US-20150112116-A1 TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM OXFORD FINANCE LLC, AS COLLATERAL AGENT 2015-04-23 US claimed
US-20150110735-A1 HIGH-SPEED CENTRIFUGAL MIXING DEVICES AND METHODS OF USE OXFORD FINANCE LLC, AS COLLATERAL AGENT 2015-04-23 US claimed
US-20150111878-A1 COMPOSITIONS AND METHODS FOR TREATING INTESTINAL HYPERPERMEABILITY HOFFMAN STEVEN (US) 2015-04-23 US claimed
US-20150111937-A1 Compositions and Methods for Treating Intestinal Hyperpermeability YAMO PHARMACEUTICALS LLC 2015-04-23 US claimed
EP-2804599-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS Tyme, Inc. (US) 2014-11-26 EP claimed
WO-2013109610-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS HOFFMAN STEVEN (US) 2013-07-25 WO claimed
US-20130184214-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS OXFORD FINANCE LLC, AS COLLATERAL AGENT 2013-07-18 US claimed
US-8481498-B1 Pharmaceutical compositions and methods OXFORD FINANCE LLC, AS COLLATERAL AGENT 2013-07-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331779-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND CALCR, BID, CASR SLC7A5 2981/4885USP2 2151/4885PTGS1 3213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.