Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043663 | 0.88 | LPL (0.40) | — | |
| SCHEMBL18174184 | 0.88 | LPL (0.40) | HTR1B | |
| SCHEMBL262784 | 0.82 | LPL (0.36) | KDM4E | |
| SCHEMBL26336096 | 0.82 | LPL (0.39) | — | |
| SCHEMBL23245014 | 0.81 | LPL (0.37) | KDM4E | |
| SCHEMBL29695363 | 0.81 | LPL (0.37) | KDM4E | |
| SCHEMBL29534512 | 0.81 | LPL (0.37) | — | |
| SCHEMBL262387 | 0.81 | LPL (0.37) | — | |
| SCHEMBL25383714 | 0.80 | KDM4E (0.45) | HRH1HTR7KDM4E | |
| SCHEMBL30674664 | 0.80 | PDK2 (0.40) | HRH1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4039280-A1 | TARGETED PYRROLOBENZODIAZEPINE CONJUGATES | Seagen Inc. (US) | 2022-08-10 | — | — | EP | disclosed |