Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.41 |
| ▸ | IL6 | P05231 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16151785 | 0.90 | MAOA (0.48) | CA12CA1CA2CA9MAOA | |
| SCHEMBL16151784 | 0.89 | MAOA (0.49) | CA12CA1CA2CA9MAOA | |
| SCHEMBL20127870 | 0.89 | MAOA (0.49) | CA12CA1CA2CA9MAOA | |
| SCHEMBL16152238 | 0.88 | MAOA (0.52) | CA12CA1CA2CA9MAOA | |
| SCHEMBL16152237 | 0.86 | MAOA (0.54) | CA12CA1CA2CA9MAOA | |
| SCHEMBL17125692 | 0.85 | MAOA (0.46) | CA12CA1CA2CA9MAOA | |
| SCHEMBL16429198 | 0.84 | CNR1 (0.46) | CNR1CNR2S1PR2S1PR1S1PR3 | |
| SCHEMBL16151781 | 0.83 | CYP3A4 (0.46) | CA1CA2MAOAMAOBTDP1 | |
| SCHEMBL16152233 | 0.82 | MAOA (0.50) | CA12CA1CA2CA9MAOA | |
| SCHEMBL16152225 | 0.82 | MAOA (0.50) | CA12CA1CA2CA9MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999345-B1 | COMPOSITIONS AND METHODS COMPRISING A POLYAMINE | CURZA GLOBAL LLC (US) | 2022-08-10 | — | — | EP | disclosed |