⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1178688 | 1.00 | — | — | |
| SCHEMBL151031 | 0.78 | — | — | |
| SCHEMBL69898 | 0.78 | — | — | |
| SCHEMBL309955 | 0.78 | — | — | |
| SCHEMBL330662 | 0.78 | — | — | |
| SCHEMBL114694 | 0.78 | — | — | |
| SCHEMBL69832 | 0.78 | — | — | |
| Parachlorophenol SCHEMBL11234434 | 0.77 | ALOX15 (0.48) | — | |
| Water SCHEMBL16553164 | 0.76 | TSHR (0.57) | — | |
| SCHEMBL29478143 | 0.76 | TSHR (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288442-A1 | UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF | Faxian Therapeutics, LLC (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022170198-A1 | UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF | FAXIAN THERAPEUTICS, LLC (US) | 2022-08-11 | — | — | WO | disclosed |
| WO-2022150584-A1 | NON-COVALENT INHIBITORS OF THE MAIN PROTEASE OF SARS-COV-2 AND METHODS OF USE | YALE UNIVERSITY (US) | 2022-07-14 | — | — | WO | disclosed |