Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29723030 | 0.92 | MME (0.48) | MMEACECPA1ACE2EGFR | |
| SCHEMBL29778417 | 0.90 | ENPEP (0.48) | MMEACECPA1ACE2ENPEP | |
| SCHEMBL30051655 | 0.88 | MME (0.54) | MMEACECPA1ACE2GLO1 | |
| SCHEMBL31571918 | 0.88 | PTGS1 (0.51) | MMEACECPA1ACE2EGFR | |
| SCHEMBL31223214 | 0.82 | ENPEP (0.54) | ENPEPBACE1 | |
| SCHEMBL12496189 | 0.81 | ENPEP (0.53) | ENPEP | |
| SCHEMBL7822201 | 0.81 | ENPEP (0.53) | ENPEP | |
| SCHEMBL12496193 | 0.81 | ENPEP (0.53) | ENPEP | |
| SCHEMBL8772366 | 0.81 | ENPEP (0.55) | ENPEPBACE1 | |
| SCHEMBL8772374 | 0.81 | ENPEP (0.55) | ENPEPBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240082183-A1 | METHODS FOR PREVENTING OR TREATING CONDITIONS RELATED TO T CELL MEDIATED INTESTINAL DISORDERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-03-14 | — | — | US | disclosed |
| WO-2022150599-A1 | METHODS FOR PREVENTING OR TREATING CONDITIONS RELATED TO T CELL MEDIATED INTESTINAL DISORDERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-07-14 | — | — | WO | disclosed |