Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112 | 1.00 | GRK6 (1.00) | GRK6GAAMAPTMCL1KMT2A | |
| Hydrochloric Acid SCHEMBL11423019 | 0.98 | GRK6 (0.96) | GRK6GAAMAPTMCL1KMT2A | |
| Bromide SCHEMBL31741343 | 0.98 | GRK6 (0.96) | GRK6GAAMAPTMCL1KMT2A | |
| Formaldehyde SCHEMBL27694578 | 0.94 | GRK6 (0.89) | GRK6GAAMAPTMCL1KMT2A | |
| Benzoquinone SCHEMBL28256504 | 0.89 | GRK6 (0.80) | GRK6GAAMAPTMCL1KMT2A | |
| Acetic Acid SCHEMBL15018560 | 0.88 | GRK6 (0.77) | GRK6GAAMAPTMCL1KMT2A | |
| SCHEMBL27746989 | 0.87 | GRK6 (0.75) | GRK6GAAMAPTMCL1KMT2A | |
| SCHEMBL27475210 | 0.87 | GRK6 (0.75) | GRK6GAAMAPTMCL1KMT2A | |
| Phenanthroline SCHEMBL23829939 | 0.85 | GRK6 (0.73) | GRK6GAAMAPTMCL1KMT2A | |
| Phenoxazine SCHEMBL27858947 | 0.84 | GRK6 (0.71) | GRK6GAAMAPTMCL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003302-A | Orally administered combination of amoxicillin and avibactam derivatives for the treatment of mycobacterial infections | ARIXA制药公司 | 2022-09-02 | — | — | CN | disclosed |