SCHEMBL8112

SCHEMBL8112

C1=Nc2cccc3cccc(c23)N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRK6 P43250 1/20 1.00
GAA P10253 11/20 0.47
MAPT P10636 9/20 0.47
MCL1 Q07820 3/20 0.47
KMT2A Q03164 10/20 0.43
MEN1 O00255 9/20 0.43
LMNA P02545 4/20 0.43
KDM4E B2RXH2 3/20 0.43
USP2 O75604 2/20 0.43
APAF1 O14727 1/20 0.43
PLCG1 P19174 1/20 0.43
CCR6 P51684 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
NPC1 O15118 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2D6 P10635 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29778809 1.00 GRK6 (1.00) GRK6GAAMAPTMCL1KMT2A
Hydrochloric Acid SCHEMBL11423019 0.98 GRK6 (0.96) GRK6GAAMAPTMCL1KMT2A
Bromide SCHEMBL31741343 0.98 GRK6 (0.96) GRK6GAAMAPTMCL1KMT2A
Formaldehyde SCHEMBL27694578 0.94 GRK6 (0.89) GRK6GAAMAPTMCL1KMT2A
Benzoquinone SCHEMBL28256504 0.89 GRK6 (0.80) GRK6GAAMAPTMCL1KMT2A
Acetic Acid SCHEMBL15018560 0.88 GRK6 (0.77) GRK6GAAMAPTMCL1KMT2A
SCHEMBL27746989 0.87 GRK6 (0.75) GRK6GAAMAPTMCL1KMT2A
SCHEMBL27475210 0.87 GRK6 (0.75) GRK6GAAMAPTMCL1KMT2A
Phenanthroline SCHEMBL23829939 0.85 GRK6 (0.73) GRK6GAAMAPTMCL1KMT2A
Phenoxazine SCHEMBL27858947 0.84 GRK6 (0.71) GRK6GAAMAPTMCL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8791 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12366813-B2 Electrophotographic photoreceptor, process cartridge and image-forming apparatus including electrophotographic photoreceptor SHARP KABUSHIKI KAISHA (JP) 2025-07-22 US claimed
WO-2025099313-A1 REDUCING BACKGROUND FLUORESCENCE IN SINGLE MOLECULE FLUORESCENCE IN SITU HYBRIDIZATION APPLICATIONS RESOLVE BIOSCIENCES GMBH (DE) 2025-05-15 WO claimed
US-12133453-B2 Polymer, composition for organic electroluminescent element, organic electroluminescent element, organic EL display device, organic EL lighting, and manufacturing method for organic electroluminescent element MITSUBISHI CHEMICAL CORPORATION (JP) 2024-10-29 US claimed
CN-118459730-A Charge-transporting compound, composition containing charge-transporting compound, and organic electroluminescent element using same 三菱化学株式会社 2024-08-09 CN claimed
US-12038593-B2 Near-infrared ray absorbing article and an optical apparatus comprising the same LMS CO., LTD. (KR) 2024-07-16 US claimed
US-12037477-B2 Near-infrared ray absorbing article and optical apparatus comprising the same LMS CO., LTD. (KR) 2024-07-16 US claimed
WO-2024102758-A2 N-(N-AMINOALKYL)PHENANTHRIDIUNIUM SERIES OF CHLORIDE-SENSITIVE FLUOROPHORES AND METHODS OF USE THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2024-05-16 WO claimed
CN-111094385-B Charge-transporting compound, composition containing charge-transporting compound, and organic electroluminescent element using same 三菱化学株式会社 2024-04-09 CN claimed
US-20240107870-A1 POLYMER, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY DEVICE, ORGANIC EL LIGHTING, AND MANUFACTURING METHOD FOR ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2024-03-28 US claimed
CN-113454141-B Polymer, organic electroluminescent element, organic EL display device, and organic EL illumination 三菱化学株式会社 2024-03-26 CN claimed
EP-0084208-B1 ASYMMETRIC DICHROIC DYE MOLECULES HAVING POLYAZOARYL LINKING GROUPS AND SUBSTITUTED ARYL THIAZYL SUBSTITUENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-11-26 EP claimed
US-4565424-A Asymmetric dichroic dye molecules having poly(arylazo) linking groups, a bis-substituted aryl thiazyl end group, and another end group MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-01-21 US claimed
EP-0084208-A2 Asymmetric dichroic dye molecules having polyazoaryl linking groups and substituted aryl thiazyl substituents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-07-27 EP claimed
US-4145215-A PHOTOCONDUCTIVE PIGMENTS EASTMAN KODAK COMPANY (US) 1979-03-20 US claimed
US-4094811-A REDUCING SILVER SALTS IN THE PRESENCE OF A HETEROCYCLIC 5- OR 6-MEMBERED NITROGEN COMPOUND AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) 1978-06-13 US claimed
US-3985880-A ANTIULCER AGENTS MCNEIL LABORATORIES, INCORPORATED (US) 1976-10-12 US claimed
US-3966933-A ANTIULCER AGENTS NCNEIL LABORATORIES, INCORPORATED (US) 1976-06-29 US claimed
US-3957993-A ADMINISTERING MCNEIL LABORATORIES, INCORPORATED (US) 1976-05-18 US claimed
US-3957991-A ADMINISTERING MCNEIL LABORATORIES, INCORPORATED (US) 1976-05-18 US claimed
US-3956497-A ANTISECRETORY AGENTS MCNEIL LABORATORIES, INCORPORATED (US) 1976-05-11 US claimed