SCHEMBL29779

SCHEMBL29779

N[C@@H](C(=O)O)C(Cl)c1ccc(O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.44
NR1I2 O75469 1/20 0.44
PTGS1 P23219 1/20 0.44
ADRA1A P35348 1/20 0.44
LMNA P02545 1/20 0.44
BLM P54132 1/20 0.44
SRC P12931 1/20 0.44
SLC7A5 Q01650 1/20 0.44
KMT2A Q03164 5/20 0.42
MEN1 O00255 4/20 0.42
CYP2C9 P11712 4/20 0.42
CYP2D6 P10635 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 1/20 0.41
GRM8 O00222 1/20 0.41
GRM4 Q14833 1/20 0.41
SLC1A3 P43003 2/20 0.40
SLC1A2 P43004 2/20 0.40
SLC1A1 P43005 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28513 1.00 TDP1 (0.44) TDP1NR1I2PTGS1ADRA1ALMNA
Hydrochloric Acid SCHEMBL28838130 0.98 TDP1 (0.43) TDP1NR1I2PTGS1ADRA1ALMNA
SCHEMBL6807352 0.83 CYP2D6 (0.48) LMNASRCCYP2D6SLC1A3SLC1A2
SCHEMBL14935796 0.83 CYP2D6 (0.48) LMNASRCCYP2D6SLC1A3SLC1A2
SCHEMBL6947260 0.83 CYP2D6 (0.48) LMNASRCCYP2D6SLC1A3SLC1A2
Hydrochloric Acid SCHEMBL8695663 0.82 CYP2D6 (0.46) LMNASRCCYP2D6SLC1A3SLC1A2
Methane SCHEMBL4340079 0.82 CYP2D6 (0.46) LMNASRCCYP2D6SLC1A3SLC1A2
SCHEMBL22074716 0.79 TDP1 (0.67) TDP1NR1I2PTGS1ADRA1ALMNA
SCHEMBL304041 0.79 TDP1 (0.47) TDP1NR1I2PTGS1ADRA1ALMNA
SCHEMBL16826249 0.79 TDP1 (0.47) TDP1NR1I2PTGS1ADRA1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331779-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND SHAANXI MICOT TECHNOLOGY CO., LTD. (CN) 2023-10-19 US claimed
EP-4212542-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND Shaanxi Micot Technology Limited Company (CN) 2023-07-19 EP claimed
CN-115087662-A Bispecific fusion polypeptide compounds 陕西麦科奥特科技有限公司 2022-09-20 CN claimed
WO-2022052471-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND 陕西麦科奥特科技有限公司 2022-03-17 WO claimed
US-20230331779-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND SHAANXI MICOT TECHNOLOGY CO., LTD. (CN) 2023-10-19 US disclosed
CN-115087662-B Bispecific fusion polypeptide compounds 陕西麦科奥特科技有限公司 2023-09-26 CN disclosed
EP-4212542-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND Shaanxi Micot Technology Limited Company (CN) 2023-07-19 EP disclosed
CN-115087662-A Bispecific fusion polypeptide compounds 陕西麦科奥特科技有限公司 2022-09-20 CN disclosed
WO-2022052471-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND 陕西麦科奥特科技有限公司 2022-03-17 WO disclosed
US-20160376579-A1 NEW ENZYMES AND METHOD FOR PREPARING 4-HYDROXYL BENZYL ALCOHOL AND DERIVATIVES THEREOF COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2016-12-29 US disclosed
EP-3083972-A2 NEW ENZYMES AND METHOD FOR PREPARING 4-HYDROXYL BENZYL ALCOHOL AND DERIVATIVES THEREOF Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2016-10-26 EP disclosed
WO-2015091755-A2 NEW ENZYMES AND METHOD FOR PREPARING 4-HYDROXYL BENZYL ALCOHOL AND DERIVATIVES THEREOF COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-06-25 WO disclosed
EP-2886656-A1 New enzyme and method for preparing 4-hydroxyl benzyl alcohol and derivatives thereof COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-06-24 EP disclosed
WO-2012025464-A1 FLUORODEUTERIOMETHYL TYROSINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331779-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND CALCR, BID, CASR TDP1 4853/4885NR1I2 2033/4885PTGS1 3213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.