Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16826249 | 1.00 | TDP1 (0.47) | TDP1NR1I2PTGS1ADRA1ALMNA | |
| SCHEMBL6046193 | 1.00 | TDP1 (0.47) | TDP1NR1I2PTGS1ADRA1ALMNA | |
| Hydrochloric Acid SCHEMBL304141 | 0.98 | TDP1 (0.46) | TDP1NR1I2PTGS1ADRA1ALMNA | |
| Hydrochloric Acid SCHEMBL9765211 | 0.98 | TDP1 (0.46) | TDP1NR1I2PTGS1ADRA1ALMNA | |
| Water SCHEMBL7731941 | 0.98 | TDP1 (0.46) | TDP1NR1I2PTGS1ADRA1ALMNA | |
| Hydrochloric Acid SCHEMBL6952165 | 0.96 | TDP1 (0.44) | TDP1NR1I2PTGS1ADRA1ALMNA | |
| Tyrosine SCHEMBL18301522 | 0.85 | SLC7A5 (0.75) | TDP1PTGS1LMNASLC7A5KMT2A | |
| SCHEMBL17477275 | 0.83 | ESR1 (0.52) | TDP1PTGS1ADRA1ALMNABLM | |
| SCHEMBL8607150 | 0.83 | ESR1 (0.52) | TDP1PTGS1ADRA1ALMNABLM | |
| SCHEMBL17477274 | 0.83 | ESR1 (0.52) | TDP1PTGS1ADRA1ALMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 820 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600699-B2 | Thiosemicarbazates and uses thereof | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-04-14 | — | — | US | claimed |
| EP-4644570-A1 | HELICASE MUTANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN HIGH-THROUGHPUT SEQUENCING | BGI Shenzhen (CN) | 2025-11-05 | — | — | EP | claimed |
| US-20250243472-A1 | MODIFIED HELICASES | OXFORD NANOPORE TECHNOLOGIES PLC (GB) | 2025-07-31 | — | — | US | claimed |
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2025-07-08 | — | — | US | claimed |
| WO-2025094171-A1 | SUPERHYDROPHOBIC COATING | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2025-05-08 | — | — | WO | claimed |
| WO-2024241086-A1 | PEGYLATED BOVINE INTERFERON LAMBDA AND METHODS OF USE THEREOF | AMBRX, INC. (US) | 2024-11-28 | — | — | WO | claimed |
| CN-118406439-B | Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing | 万华化学集团电子材料有限公司 | 2024-10-18 | — | — | CN | claimed |
| WO-2024215515-A1 | DRUG LINKERS AND ANTIBODY CONJUGATES THEREOF | AMBRX, INC. (US) | 2024-10-17 | — | — | WO | claimed |
| WO-2024178310-A1 | TROP2-DIRECTED ANTIBODY-DRUG CONJUGATES AND USES THEREOF | AMBRX, INC. (US) | 2024-08-29 | — | — | WO | claimed |
| CN-118406439-A | Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing | 万华化学集团电子材料有限公司 | 2024-07-30 | — | — | CN | claimed |
| US-5902728-A | BIOSYNTHESIS OF DIAZOLUMINOMELANIN BY CULTURING ESCHERICHIA COLI TRANSFECTED WITH PLASMID CONTAINING BARLEY NITRATE REDUCTASE IN MEDIA WITH NITRATE, 3-AMINO-L-TYROSINE, AND LUMINOL; FOR SCREENING OF CHEMICAL AND RADIATION STRESSORS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1999-05-11 | — | — | US | claimed |
| US-5856108-A | CULTURE PRODUCT USING A NITRATE, 3-AMINO-L-TYROSINE, LUMINOL UNDER METABOLIC CONDITIONS USING REDUCTASE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1999-01-05 | — | — | US | claimed |
| US-5658673-A | SUBSTRATE CONTAINING ACTIVATED DIAZOLUMINOMELANIN; RADIATION DETECTOR | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1997-08-19 | — | — | US | claimed |
| US-5340734-A | In vitro biosynthesis the melanins in presence of a substrate consisting of tyrosine binding single amino acid, a dipeptide or an oligopeptide | BIOSOURCE GENETICS CORPORATION (US) | 1994-08-23 | — | — | US | claimed |
| US-5310539-A | Paramagnetic rare earth metals, magnetic resonance imaging | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-05-10 | — | — | US | claimed |
| EP-0580734-A1 | MELANIN-BASED AGENTS FOR IMAGE ENHANCEMENT | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-02-02 | — | — | EP | claimed |
| WO-1992018166-A1 | MELANIN-BASED AGENTS FOR IMAGE ENHANCEMENT | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-10-29 | — | — | WO | claimed |
| US-5156971-A | Rapid identification of environmental bacillus | AIR FORCE, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE | 1992-10-20 | — | — | US | claimed |
| US-5003050-A | Diazoluminomelanin and a method for preparing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1991-03-26 | — | — | US | claimed |
| US-4870002-A | 3-AMINO-L-TYROSINE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1989-09-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | DNPEP, NPEPPS, PAM | TDP1 3027/4885NR1I2 4566/4885PTGS1 2925/4885 |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | MET, THRB, ABAT | TDP1 2893/4885NR1I2 2038/4885PTGS1 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.