Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 18/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 18/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 18/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23167670 | 1.00 | HDAC6 (0.55) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL29779612 | 0.85 | VNN1 (0.41) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL23167429 | 0.85 | VNN1 (0.41) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL23167384 | 0.80 | HDAC6 (0.76) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL23203204 | 0.79 | HDAC6 (0.46) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL23202606 | 0.73 | HDAC6 (0.65) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL23202801 | 0.73 | HDAC6 (0.56) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL23202585 | 0.72 | HDAC6 (0.49) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL4730434 | 0.71 | HDAC3 (1.00) | HDAC6HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL25138289 | 0.71 | HDAC6 (0.47) | HDAC6HDAC3HDAC1HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037670-A1 | 5-FLUORONICOTINAMIDE DERIVATIVES AND USES THEREOF | Tenaya Therapeutics, Inc. (US) | 2022-08-10 | — | — | EP | disclosed |