Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CBX7 | O95931 | 2/20 | 0.44 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.44 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.44 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23166446 | 1.00 | CHRM1 (0.49) | CHRM1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL25138325 | 0.81 | HDAC6 (0.54) | ALDH1A1MAPTTSHRGRM5HDAC1 | |
| SCHEMBL23202576 | 0.77 | HDAC6 (0.43) | CHRM1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL18581560 | 0.74 | KDM4E (0.50) | CHRM1ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL29790608 | 0.71 | BRD4 (0.55) | ALDH1A1KDM4EMAPTCBX7CDYL2 | |
| SCHEMBL18581748 | 0.71 | BRD4 (0.55) | ALDH1A1KDM4EMAPTCBX7CDYL2 | |
| SCHEMBL18581471 | 0.71 | CBX7 (0.46) | ALDH1A1KDM4EMAPTCBX7CDYL2 | |
| SCHEMBL29790714 | 0.71 | CBX7 (0.46) | ALDH1A1KDM4EMAPTCBX7CDYL2 | |
| SCHEMBL23201987 | 0.71 | HDAC6 (0.45) | ALDH1A1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL18581373 | 0.71 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037670-A1 | 5-FLUORONICOTINAMIDE DERIVATIVES AND USES THEREOF | Tenaya Therapeutics, Inc. (US) | 2022-08-10 | — | — | EP | disclosed |