Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29779702 | 1.00 | MAOB (0.47) | MAOBADORA2AADORA1IDO1MEN1 | |
| SCHEMBL19554588 | 1.00 | MAOB (0.47) | MAOBADORA2AADORA1IDO1MEN1 | |
| SCHEMBL10835499 | 0.83 | MAOB (0.49) | MAOBIDO1MEN1KMT2AMGAM | |
| SCHEMBL29779696 | 0.81 | NPC1 (0.41) | MAOBADORA2AADORA1MEN1MAPT | |
| SCHEMBL19554487 | 0.81 | NPC1 (0.41) | MAOBADORA2AADORA1MEN1MAPT | |
| SCHEMBL30962961 | 0.80 | CASP1 (0.53) | MAOBMEN1MAPTKMT2AKDM4E | |
| SCHEMBL581917 | 0.80 | CASP1 (0.53) | MAOBMEN1MAPTKMT2AKDM4E | |
| SCHEMBL19555195 | 0.80 | KDM4E (0.49) | MAOBADORA2AADORA1IDO1MEN1 | |
| SCHEMBL10835376 | 0.80 | MAOB (0.50) | MAOBIDO1MEN1KMT2AKDM4E | |
| SCHEMBL29779684 | 0.78 | MAOB (0.51) | MAOBMEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311902-B | Substituted imidazo [1,2-b ] pyridazines, imidazo [1,5-b ] pyridazines, related compounds, and uses thereof | BIAL研发投资股份有限公司 | 2022-07-15 | — | — | CN | disclosed |