Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726714 | 0.84 | GAA (0.48) | DHODHKDM4EALDH1A1GLAGAA | |
| SCHEMBL29781369 | 0.84 | MAP2K1 (0.60) | DHODHKDM4EALDH1A1GLAGAA | |
| SCHEMBL3885464 | 0.84 | MAP2K1 (0.60) | DHODHKDM4EALDH1A1GLAGAA | |
| SCHEMBL23673877 | 0.82 | MAP2K1 (0.37) | DHODHKDM4EALDH1A1GAANUDT1 | |
| SCHEMBL29425395 | 0.81 | KDM4E (0.43) | DHODHKDM4EMAP2K1L3MBTL1MAPK14 | |
| SCHEMBL23673984 | 0.81 | KDM4E (0.43) | DHODHKDM4EMAP2K1L3MBTL1MAPK14 | |
| SCHEMBL3732479 | 0.81 | KDM4E (0.50) | DHODHKDM4EALDH1A1GLAGAA | |
| SCHEMBL23673897 | 0.79 | MAPK14 (0.34) | DHODHKDM4EALDH1A1NUDT1MAP2K1 | |
| SCHEMBL23673990 | 0.79 | MAP2K1 (0.35) | DHODHKDM4ENUDT1MAP2K2MAP2K1 | |
| SCHEMBL30459905 | 0.79 | MAP2K1 (0.35) | DHODHKDM4ENUDT1MAP2K2MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929669-A | Arylamide derivatives having antitumor activity | 中外制药株式会社 | 2022-08-19 | — | — | CN | disclosed |