SCHEMBL297822

SCHEMBL297822

Cc1cc(C2(c3cc(C)c(O)c(Cl)c3)CCCCC2)cc(Cl)c1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.76
ESR1 P03372 4/20 0.54
ESR2 Q92731 4/20 0.54
ALOX12 P18054 4/20 0.40
LMNA P02545 3/20 0.40
ALDH1A1 P00352 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
MPI P34949 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PPARA Q07869 1/20 0.36
SLC6A2 P23975 7/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10787766 1.00 ACHE (0.76) ACHEESR1ESR2ALOX12LMNA
SCHEMBL10799203 1.00 ACHE (0.76) ACHEESR1ESR2ALOX12LMNA
SCHEMBL30442737 1.00 ACHE (0.76) ACHEESR1ESR2ALOX12LMNA
SCHEMBL8410883 0.91 ACHE (0.60) ACHEESR1ESR2ALOX12ALDH1A1
SCHEMBL672596 0.87 ACHE (1.00) ACHEESR1ESR2ALOX12LMNA
SCHEMBL675004 0.87 ACHE (1.00) ACHEESR1ESR2ALOX12LMNA
SCHEMBL673424 0.87 ACHE (1.00) ACHEESR1ESR2ALOX12LMNA
SCHEMBL10941758 0.87 ACHE (1.00) ACHEESR1ESR2ALOX12LMNA
SCHEMBL674887 0.87 ACHE (1.00) ACHEESR1ESR2ALOX12LMNA
SCHEMBL673355 0.87 ACHE (1.00) ACHEESR1ESR2ALOX12LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
EP-1560871-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-08-10 EP claimed
WO-2004041907-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-05-21 WO claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
US-4223170-A HEAT DISTORTION RESISTANT POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 1980-09-16 US claimed
US-11898025-B2 Polyethylene with additives for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-02-13 US disclosed
US-11535732-B2 Polyethylene with polycarbonate-siloxane for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-12-27 US disclosed
US-20210388189-A1 POLYETHYLENE WITH ADDITIVES FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-16 US disclosed
US-20210309839-A1 POLYETHYLENE WITH POLYCARBONATE-SILOXANE FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-10-07 US disclosed
US-4579903-A SOLVENT, HEAT RESISTANT; BLENDED WITH VINYL AROMATIC AND OLEFIN ELASTOMER BLOCK POLYMERS, EPOMTER GENERAL ELECTRIC COMPANY (US) 1986-04-01 US disclosed
US-4559388-A BLEND WITH ADDITION POLYMERS TO IMPROVE SOLVENT AND IMPACT RESISTANCES; ENGINEERING THERMOPLASTICS; WINDSHEILDS GENERAL ELECTRIC COMPANY (US) 1985-12-17 US disclosed
US-4223170-A HEAT DISTORTION RESISTANT POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 1980-09-16 US disclosed
US-4195157-A HALOGENATED GENERAL ELECTRIC COMPANY (US) 1980-03-25 US disclosed
US-4180651-A Polycarbonate composition having resistance to high heat distortion GENERAL ELECTRIC COMPANY (US) 1979-12-25 US disclosed