Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20916386 | 1.00 | MAPT (0.47) | MAPTRAB9ANPC1HPGDGFER | |
| SCHEMBL20916370 | 0.82 | GRM2 (0.49) | MAPTRAB9ANPC1CYP2C9KMT2A | |
| SCHEMBL12310543 | 0.73 | MAPK1 (0.51) | MAPTRAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL20916401 | 0.71 | MAPT (0.46) | MAPTRAB9ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19551760 | 0.71 | CA12 (0.44) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29782343 | 0.71 | MAPT (0.46) | MAPTRAB9ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29718815 | 0.69 | PTGS2 (0.51) | MAPTCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL19552387 | 0.69 | PTGS2 (0.51) | MAPTCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL19552590 | 0.69 | P2RX4 (0.56) | ALDH1A1 | |
| SCHEMBL20916434 | 0.69 | CA12 (0.42) | MAPTCYP3A4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114984003-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-115054600-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-115054600-A | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114984003-A | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2022-09-02 | — | — | CN | disclosed |