Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20853431 | 1.00 | BTK (0.53) | BTKCTSLCTSBCTSK | |
| SCHEMBL17707883 | 1.00 | BTK (0.53) | BTKCTSLCTSBCTSK | |
| SCHEMBL20863093 | 0.87 | BTK (0.54) | BTKCTSLCTSBCTSK | |
| SCHEMBL17707905 | 0.87 | BTK (0.54) | BTKCTSLCTSBCTSK | |
| SCHEMBL29782655 | 0.87 | BTK (0.54) | BTKCTSLCTSBCTSK | |
| SCHEMBL17699921 | 0.87 | BTK (0.60) | BTK | |
| SCHEMBL21509051 | 0.86 | CTSL (0.47) | BTKCTSLCTSBCTSK | |
| SCHEMBL19715369 | 0.86 | CTSL (0.47) | BTKCTSLCTSBCTSK | |
| SCHEMBL146149 | 0.83 | CTSL (0.46) | BTKCTSLCTSBCTSK | |
| SCHEMBL146148 | 0.83 | CTSL (0.46) | BTKCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511209-B | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2022-07-05 | — | — | CN | disclosed |