SCHEMBL29782876

SCHEMBL29782876

C[Si](C)(C)CCOCn1ccc2c(Br)ccc(C(N)=O)c21

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.39
DGAT1 O75907 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17699642 1.00 NPC1 (0.39) NPC1DGAT1
SCHEMBL12566360 0.89 DGAT1 (0.34) NPC1DGAT1
SCHEMBL16382758 0.89 DGAT1 (0.34) NPC1DGAT1
SCHEMBL12567426 0.88 DGAT1 (0.34) NPC1DGAT1
SCHEMBL12566361 0.87 DGAT1 (0.33) NPC1DGAT1
SCHEMBL12566362 0.87 DGAT1 (0.33) NPC1DGAT1
SCHEMBL1076270 0.84 DGAT1 (0.39) NPC1DGAT1
SCHEMBL16337272 0.80 NPC1 (0.44) NPC1DGAT1
SCHEMBL17699550 0.80 DGAT1 (0.37) NPC1DGAT1
SCHEMBL29782740 0.80 DGAT1 (0.37) NPC1DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110511209-B Indole carboxamide compounds useful as kinase inhibitors 百时美施贵宝公司 2022-07-05 CN disclosed