Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ADA | P00813 | 4/20 | 0.39 |
| ▸ | PDE2A | O00408 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596724 | 0.88 | ADORA2A (0.50) | ADORA2AADORA2BADORA1FDPSPI4KA | |
| SCHEMBL11596855 | 0.83 | ADORA2A (0.51) | ADORA2AADORA2BADORA1FDPSPI4KA | |
| SCHEMBL29782775 | 0.83 | FDPS (0.45) | ADORA2AADORA2BADORA1FDPSPI4KA | |
| SCHEMBL29782858 | 0.82 | FDPS (0.47) | ADORA2AADORA2BADORA1FDPSPI4KA | |
| SCHEMBL27459321 | 0.81 | ADORA2A (0.44) | ADORA2AADORA2BADORA1FDPSPI4KA | |
| SCHEMBL29782820 | 0.80 | ADA (0.43) | ADORA2AADORA2BADORA1FDPSFGFR1 | |
| SCHEMBL11258096 | 0.80 | ADORA2A (0.47) | ADORA2AADORA2BADORA1FDPSPI4KA | |
| SCHEMBL11597675 | 0.79 | FDPS (0.44) | ADORA2AADORA2BADORA1FDPSPI4KA | |
| SCHEMBL31331738 | 0.79 | ADORA2A (0.64) | ADORA2AADORA2BADORA1FDPSPI4KA | |
| SCHEMBL2475932 | 0.79 | ADORA2A (0.64) | ADORA2AADORA2BADORA1FDPSPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574217-B | Acyclic nucleoside lead compound, preparation method thereof and application thereof in pharmacy | 河南师范大学 | 2022-05-20 | — | — | CN | disclosed |