Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.63 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.63 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5911613 | 0.90 | EGFR (0.73) | EGFRAURKBERBB2KDRHDAC3 | |
| SCHEMBL30279467 | 0.90 | EGFR (0.73) | EGFRAURKBERBB2KDRHDAC3 | |
| SCHEMBL26916514 | 0.88 | EGFR (0.62) | EGFRAURKBERBB2KDRHDAC3 | |
| SCHEMBL29274505 | 0.88 | EGFR (0.60) | EGFRAURKBERBB2KDRHDAC3 | |
| SCHEMBL4577613 | 0.87 | EGFR (0.72) | EGFRAURKBERBB2KDRHDAC3 | |
| SCHEMBL17538491 | 0.85 | EGFR (0.60) | EGFRAURKBERBB2KDRHDAC3 | |
| SCHEMBL1446582 | 0.84 | EGFR (0.64) | EGFRAURKBERBB2KDR | |
| SCHEMBL29782920 | 0.83 | EGFR (0.65) | EGFRERBB2KDR | |
| SCHEMBL28538015 | 0.83 | EGFR (0.61) | EGFRAURKBERBB2KDR | |
| SCHEMBL30119557 | 0.83 | EGFR (0.61) | EGFRAURKBERBB2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240410876-A1 | EXTRACELLULAR VESICLE DRUG ANALYSIS FOR REAL-TIME MONITORING OF TARGETED THERAPY | NAT UNIV SINGAPORE (SG) | 2024-12-12 | — | — | US | disclosed |
| WO-2022168055-A1 | EXTRACELLULAR VESICLE DRUG ANALYSIS FOR REAL-TIME MONITORING OF TARGETED THERAPY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2022-08-11 | — | — | WO | disclosed |