Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 4/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | TNKS | O95271 | 2/20 | 0.73 |
| ▸ | PARP1 | P09874 | 2/20 | 0.73 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.73 |
| ▸ | CASP3 | P42574 | 1/20 | 0.73 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.73 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.73 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874228 | 1.00 | GUSB (0.73) | GUSBNPC1RAB9ATNKSPARP1 | |
| SCHEMBL28645325 | 0.89 | GUSB (0.77) | GUSBNPC1RAB9ATNKSPARP1 | |
| SCHEMBL27694110 | 0.86 | NPC1 (0.61) | GUSBNPC1RAB9ATNKSPARP1 | |
| SCHEMBL8620410 | 0.85 | TNKS (0.83) | GUSBNPC1RAB9ATNKSPARP1 | |
| SCHEMBL13011773 | 0.85 | GUSB (0.75) | GUSBNPC1RAB9ATNKSPARP1 | |
| SCHEMBL17786622 | 0.85 | NPC1 (0.59) | GUSBNPC1RAB9ATNKSPARP1 | |
| SCHEMBL259622 | 0.85 | KDM4C (0.55) | GUSBNPC1RAB9ATNKSPARP1 | |
| SCHEMBL27694097 | 0.85 | TNKS (0.58) | GUSBNPC1RAB9ATNKSPARP1 | |
| SCHEMBL259479 | 0.85 | ALDH1A1 (0.64) | GUSBNPC1RAB9ATNKSPARP1 | |
| SCHEMBL259476 | 0.85 | KDM4C (0.66) | GUSBNPC1RAB9ATNKSPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359548-A | Preparation method of benzodiazepine compound | 重庆医科大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-113563272-B | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-109879820-B | Synthetic method of quinazolinone heterocyclic compound | 扬州大学 | 2022-07-19 | — | — | CN | disclosed |