Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 5/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27185530 | 1.00 | STING1 (0.50) | STING1KDM4AHPGDUSP2POLB | |
| SCHEMBL27185593 | 0.90 | STING1 (0.43) | STING1KDM4AACACBACACAGAA | |
| SCHEMBL29784337 | 0.90 | STING1 (0.43) | STING1KDM4AACACBACACAGAA | |
| SCHEMBL29784270 | 0.87 | MAPT (0.40) | STING1KDM4AHPGDALOX15CASP1 | |
| SCHEMBL27185727 | 0.87 | MAPT (0.40) | STING1KDM4AHPGDALOX15CASP1 | |
| SCHEMBL29784379 | 0.84 | STING1 (0.46) | STING1KDM4AACACBACACAGAA | |
| SCHEMBL27185404 | 0.84 | STING1 (0.46) | STING1KDM4AACACBACACAGAA | |
| SCHEMBL29784414 | 0.82 | NSD2 (0.37) | STING1KDM4AGPR35GAA | |
| SCHEMBL19079895 | 0.79 | HPGD (0.43) | KDM4AHPGDPOLBCASP1CASP7 | |
| SCHEMBL27185764 | 0.78 | MAPT (0.39) | KDM4AHPGDALOX15CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169921-A1 | BENZOFURAN COMPOUNDS AS STING AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-08-11 | — | — | WO | disclosed |