Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 5/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27185593 | 1.00 | STING1 (0.43) | STING1ATRKDM4AALDH1A1GAA | |
| SCHEMBL29784277 | 0.90 | STING1 (0.50) | STING1KDM4AALDH1A1GAAKCNA5 | |
| SCHEMBL27185530 | 0.90 | STING1 (0.50) | STING1KDM4AALDH1A1GAAKCNA5 | |
| SCHEMBL29784379 | 0.87 | STING1 (0.46) | STING1KDM4AALDH1A1GAAKCNA5 | |
| SCHEMBL27185404 | 0.87 | STING1 (0.46) | STING1KDM4AALDH1A1GAAKCNA5 | |
| SCHEMBL29784263 | 0.87 | STING1 (0.42) | STING1ATRKDM4AALDH1A1GAA | |
| SCHEMBL29784510 | 0.87 | ALDH1A1 (0.40) | STING1ATRKDM4AALDH1A1GAA | |
| SCHEMBL27185785 | 0.87 | ALDH1A1 (0.40) | STING1ATRKDM4AALDH1A1GAA | |
| SCHEMBL29784449 | 0.87 | ESR2 (0.40) | STING1ATRKDM4AALDH1A1GAA | |
| SCHEMBL27185758 | 0.87 | ESR2 (0.40) | STING1ATRKDM4AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169921-A1 | BENZOFURAN COMPOUNDS AS STING AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-08-11 | — | — | WO | disclosed |