Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28765277 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19HTR2CPSEN1PSEN2 | |
| SCHEMBL29786253 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19HTR2CPSEN1PSEN2 | |
| SCHEMBL29786254 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19HTR2CPSEN1PSEN2 | |
| SCHEMBL20791067 | 0.89 | HTR2C (0.52) | SMN1; SMN2CYP2C19HTR2CPSEN1PSEN2 | |
| SCHEMBL26397763 | 0.89 | HTR2C (0.52) | SMN1; SMN2CYP2C19HTR2CPSEN1PSEN2 | |
| SCHEMBL7345709 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19HTR2CPSEN1PSEN2 | |
| SCHEMBL28453965 | 0.84 | HTR2C (0.50) | SMN1; SMN2CYP2C19HTR2CPSEN1PSEN2 | |
| SCHEMBL26397760 | 0.84 | HTR2C (0.50) | SMN1; SMN2CYP2C19HTR2CPSEN1PSEN2 | |
| SCHEMBL19042 | 0.78 | ACE (0.53) | SMN1; SMN2CYP2C19HTR2CNPC1RAB9A | |
| SCHEMBL7339038 | 0.78 | ACE (0.53) | SMN1; SMN2CYP2C19HTR2CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110339079-B | Composition comprising amide derivatives and use thereof in cosmetics | 广州双慧化妆品有限公司 | 2022-05-24 | — | — | CN | claimed |
| CN-110339079-B | Composition comprising amide derivatives and use thereof in cosmetics | 广州双慧化妆品有限公司 | 2022-05-24 | — | — | CN | disclosed |