Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843206 | 0.90 | ACE (0.53) | SMN1; SMN2CYP2C19HTR2CNPC1RAB9A | |
| SCHEMBL4799717 | 0.90 | ACE (0.53) | SMN1; SMN2CYP2C19HTR2CNPC1RAB9A | |
| SCHEMBL4848858 | 0.90 | ACE (0.53) | SMN1; SMN2CYP2C19HTR2CNPC1RAB9A | |
| SCHEMBL7339038 | 0.90 | ACE (0.53) | SMN1; SMN2CYP2C19HTR2CNPC1RAB9A | |
| SCHEMBL4842577 | 0.90 | ACE (0.53) | SMN1; SMN2CYP2C19HTR2CNPC1RAB9A | |
| SCHEMBL16276265 | 0.89 | HTR2C (0.48) | SMN1; SMN2CYP2C19HTR2CNPC1RAB9A | |
| SCHEMBL28765277 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19HTR2CNPC1RAB9A | |
| SCHEMBL29786253 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19HTR2CNPC1RAB9A | |
| SCHEMBL29786255 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19HTR2CNPC1RAB9A | |
| SCHEMBL29786254 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19HTR2CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252928-A1 | PHOSPHINYLALKANOYL IMINO ACIDS | SCHERING CORPORATION (US) | 1988-01-20 | — | — | EP | disclosed |
| EP-0224067-A1 | Phosphinylalkanoyl amino acids | SCHERING CORPORATION (US) | 1987-06-03 | — | — | EP | disclosed |
| WO-1987002669-A1 | PHOSPHINYLALKANOYL IMINO ACIDS | SCHERING CORPORATION (US) | 1987-05-07 | — | — | WO | disclosed |
| US-4634689-A | HYPOTENSIVE AGENTS | SCHERING CORPORATION (US) | 1987-01-06 | — | — | US | disclosed |