Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20472535 | 1.00 | HTR2C (0.52) | HTR2CHTR2AHTR2BNOS3NOS1 | |
| SCHEMBL30175236 | 0.94 | HTR2C (0.58) | HTR2CHTR2AHTR2BNOS3NOS1 | |
| SCHEMBL22470674 | 0.94 | HTR2C (0.58) | HTR2CHTR2AHTR2BNOS3NOS1 | |
| SCHEMBL20472606 | 0.89 | HTR2C (0.50) | HTR2CHTR2AHTR2BNOS3NOS1 | |
| SCHEMBL29786395 | 0.89 | HTR2C (0.50) | HTR2CHTR2AHTR2BNOS3NOS1 | |
| SCHEMBL20472348 | 0.83 | HTR2C (0.56) | HTR2CHTR2AHTR2BNOS3NOS1 | |
| SCHEMBL29786681 | 0.83 | HTR2C (0.56) | HTR2CHTR2AHTR2BNOS3NOS1 | |
| SCHEMBL6213774 | 0.82 | SLC6A4 (0.54) | HTR2CHTR2BNOS3NOS1SLC6A4 | |
| SCHEMBL22957811 | 0.81 | HTR2A (0.55) | HTR2CHTR2AHTR2BSLC6A4SLC6A2 | |
| SCHEMBL22391953 | 0.81 | RIPK1 (0.61) | HTR2CHTR2AHTR2BNOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520423-B | Aminotriazolopyridines as kinase inhibitors | 百时美施贵宝公司 | 2022-08-23 | — | — | CN | disclosed |