Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20472353 | 1.00 | RIPK1 (0.54) | RIPK1MCHR1HTR2CFAAHCNR1 | |
| SCHEMBL29786424 | 0.98 | RIPK1 (0.55) | RIPK1MCHR1HTR2CFAAHCNR1 | |
| SCHEMBL20472415 | 0.98 | RIPK1 (0.55) | RIPK1MCHR1HTR2CFAAHCNR1 | |
| SCHEMBL29786364 | 0.95 | RIPK1 (0.55) | RIPK1MCHR1HTR2CFAAHCNR1 | |
| SCHEMBL20472419 | 0.95 | RIPK1 (0.55) | RIPK1MCHR1HTR2CFAAHCNR1 | |
| SCHEMBL8252603 | 0.91 | RIPK1 (0.63) | RIPK1MCHR1HTR2CNOS3NOS1 | |
| Hydrochloric Acid SCHEMBL22470881 | 0.90 | RIPK1 (0.61) | RIPK1MCHR1HTR2CNOS3NOS1 | |
| Hydrochloric Acid SCHEMBL30175221 | 0.90 | RIPK1 (0.61) | RIPK1MCHR1HTR2CNOS3NOS1 | |
| SCHEMBL20472363 | 0.84 | RIPK1 (0.59) | RIPK1MCHR1HTR2CNOS3NOS1 | |
| SCHEMBL29786590 | 0.84 | RIPK1 (0.59) | RIPK1MCHR1HTR2CNOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520423-B | Aminotriazolopyridines as kinase inhibitors | 百时美施贵宝公司 | 2022-08-23 | — | — | CN | disclosed |