Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23248025 | 0.83 | POLB (0.45) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL9628374 | 0.79 | HTT (0.43) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL31051464 | 0.76 | HSD17B10 (0.47) | MAPTKMT2AKDM4EGAAPOLB | |
| SCHEMBL9627920 | 0.72 | KDM4E (0.46) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL9641706 | 0.72 | ABCB11 (0.53) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL9627616 | 0.70 | KDM4E (0.54) | MAPTALDH1A1KDM4EGAAPOLB | |
| SCHEMBL9627620 | 0.70 | KDM4E (0.56) | MAPTALDH1A1KDM4EGAAPOLB | |
| SCHEMBL9629451 | 0.70 | KDM4E (0.54) | MAPTALDH1A1KDM4EGAAPOLB | |
| SCHEMBL9643583 | 0.69 | ABCB11 (0.46) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL3755885 | 0.68 | MAPK1 (0.56) | MAPTALDH1A1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299349-A1 | TREATMENT OR PREVENTION OF LEUKAEMIA | VESTLANDETS INNOVASJONSSELSKAP AS (NO) | 2024-09-12 | — | — | US | disclosed |
| EP-4021431-A1 | TREATMENT OR PREVENTION OF LEUKAEMIA | Vestlandets Innovasjonsselskap AS (NO) | 2022-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299349-A1 | TREATMENT OR PREVENTION OF LEUKAEMIA | BCL9, BCL9L, MCL1 | MAPT 4855/4885ALDH1A1 1073/4885KMT2A 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.