Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 6/20 | 0.62 |
| ▸ | ACACB | O00763 | 3/20 | 0.54 |
| ▸ | ACACA | Q13085 | 3/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2978736 | 1.00 | HPGDS (0.62) | HPGDSACACBACACAMAP4K4GABRA5 | |
| SCHEMBL2985636 | 0.91 | HPGDS (0.66) | HPGDSMAP4K4GABRA5GRM5USP30 | |
| SCHEMBL2994529 | 0.91 | HPGDS (0.66) | HPGDSMAP4K4GABRA5GRM5USP30 | |
| SCHEMBL2985631 | 0.91 | HPGDS (0.66) | HPGDSMAP4K4GABRA5GRM5USP30 | |
| SCHEMBL2987640 | 0.90 | HPGDS (0.57) | HPGDSACACBACACAMAP4K4HRH3 | |
| SCHEMBL2987642 | 0.90 | HPGDS (0.57) | HPGDSACACBACACAMAP4K4HRH3 | |
| SCHEMBL2984489 | 0.90 | HPGDS (0.63) | HPGDSACACBACACAMAP4K4GABRA5 | |
| SCHEMBL2984485 | 0.90 | HPGDS (0.63) | HPGDSACACBACACAMAP4K4GABRA5 | |
| SCHEMBL2996585 | 0.90 | HPGDS (0.65) | HPGDSACACBACACAMAP4K4GABRA5 | |
| SCHEMBL2996580 | 0.90 | HPGDS (0.65) | HPGDSACACBACACAMAP4K4GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173888-A1 | Nicotinamide Derivatives | PFIZER INC | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173888-A1 | Nicotinamide Derivatives | NNT, NAMPT, NQO1 | HPGDS 1073/4885ACACB 875/4885ACACA 929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.