Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 19/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29790033 | 0.93 | MAT2A (0.69) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24596151 | 0.93 | MAT2A (0.69) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29789931 | 0.83 | MAT2A (0.69) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24596218 | 0.83 | MAT2A (0.69) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29790007 | 0.83 | MAT2A (0.43) | MAT2A | |
| SCHEMBL24596183 | 0.81 | MAT2A (0.52) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29790082 | 0.81 | MAT2A (0.52) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24596223 | 0.81 | MAT2A (0.53) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24596221 | 0.81 | MAT2A (0.53) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29789949 | 0.81 | MAT2A (0.53) | MAT2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |