Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19737998 | 0.88 | NPSR1 (0.43) | NPSR1KDM4CKDM2BKDM4EAPOBEC3A | |
| SCHEMBL24596265 | 0.73 | NPSR1 (0.39) | NPSR1KDM4EAPOBEC3AAPOBEC3GL3MBTL1 | |
| SCHEMBL24596346 | 0.72 | NPSR1 (0.38) | NPSR1KDM4EMAPK1L3MBTL1MAPT | |
| SCHEMBL13651660 | 0.72 | NPSR1 (0.45) | NPSR1KDM4CKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL71364 | 0.72 | APOBEC3A (0.46) | NPSR1KDM4EAPOBEC3AAPOBEC3GL3MBTL1 | |
| SCHEMBL12255736 | 0.72 | NPSR1 (0.45) | NPSR1KDM4EAPOBEC3AAPOBEC3GL3MBTL1 | |
| SCHEMBL31336866 | 0.70 | KDM4E (0.44) | NPSR1KDM4EAPOBEC3AAPOBEC3GL3MBTL1 | |
| SCHEMBL31336864 | 0.70 | NPSR1 (0.43) | NPSR1KDM4CKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL13651652 | 0.70 | NPSR1 (0.43) | NPSR1KDM4EAPOBEC3AAPOBEC3GL3MBTL1 | |
| SCHEMBL31336867 | 0.70 | KDM4E (0.44) | NPSR1KDM4EAPOBEC3AAPOBEC3GL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |