Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12255736 | 0.79 | NPSR1 (0.45) | NPSR1APOBEC3AAPOBEC3GL3MBTL1ALDH1A1 | |
| SCHEMBL13651660 | 0.79 | NPSR1 (0.45) | NPSR1APOBEC3AAPOBEC3GL3MBTL1ALDH1A1 | |
| SCHEMBL71364 | 0.79 | APOBEC3A (0.46) | NPSR1APOBEC3AAPOBEC3GL3MBTL1ALDH1A1 | |
| SCHEMBL13651652 | 0.78 | NPSR1 (0.43) | NPSR1APOBEC3AAPOBEC3GL3MBTL1ALDH1A1 | |
| SCHEMBL31336867 | 0.78 | KDM4E (0.44) | NPSR1APOBEC3AAPOBEC3GL3MBTL1ALDH1A1 | |
| SCHEMBL2234794 | 0.78 | NPSR1 (0.43) | NPSR1APOBEC3AAPOBEC3GL3MBTL1ALDH1A1 | |
| SCHEMBL31336866 | 0.78 | KDM4E (0.44) | NPSR1APOBEC3AAPOBEC3GL3MBTL1ALDH1A1 | |
| SCHEMBL19737998 | 0.78 | NPSR1 (0.43) | NPSR1APOBEC3AAPOBEC3GL3MBTL1ALDH1A1 | |
| SCHEMBL14736244 | 0.76 | APOBEC3A (0.44) | NPSR1APOBEC3AAPOBEC3GL3MBTL1KDM4E | |
| SCHEMBL24174908 | 0.75 | NPSR1 (0.41) | NPSR1APOBEC3AAPOBEC3GL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| EP-4688155-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | Bial-Portela & CA, S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023852-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |