Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 18/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24596271 | 1.00 | MAT2A (0.54) | MAT2ACYP3A4NFKB1PMP22ALDH1A1 | |
| SCHEMBL24596318 | 0.90 | MAT2A (0.53) | MAT2A | |
| SCHEMBL31042367 | 0.85 | MAT2A (0.47) | MAT2A | |
| SCHEMBL26121301 | 0.85 | MAT2A (0.47) | MAT2A | |
| SCHEMBL24596379 | 0.83 | MAT2A (0.47) | MAT2A | |
| SCHEMBL24596266 | 0.83 | MAT2A (0.47) | MAT2ACYP3A4NFKB1PMP22 | |
| SCHEMBL26631689 | 0.82 | MAT2A (0.46) | MAT2A | |
| SCHEMBL29789990 | 0.81 | MAT2A (0.47) | MAT2AALDH1A1 | |
| SCHEMBL26631699 | 0.81 | MAT2A (0.47) | MAT2AALDH1A1 | |
| SCHEMBL31339936 | 0.80 | MAT2A (0.43) | MAT2ACYP3A4NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |