Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 17/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24596305 | 1.00 | MAT2A (0.58) | MAT2AALDH1A1KDM4ES1PR4GLA | |
| SCHEMBL24596171 | 0.91 | MAT2A (0.58) | MAT2AALDH1A1KDM4ES1PR4GLA | |
| SCHEMBL29789946 | 0.91 | MAT2A (0.58) | MAT2AALDH1A1KDM4ES1PR4GLA | |
| SCHEMBL29790042 | 0.88 | MAT2A (0.44) | MAT2A | |
| SCHEMBL24596226 | 0.88 | MAT2A (0.44) | MAT2A | |
| SCHEMBL24596249 | 0.85 | MAT2A (0.64) | MAT2A | |
| SCHEMBL29789938 | 0.85 | MAT2A (0.64) | MAT2A | |
| SCHEMBL24596270 | 0.84 | MAT2A (0.66) | MAT2A | |
| SCHEMBL29790006 | 0.84 | MAT2A (0.66) | MAT2A | |
| SCHEMBL24596366 | 0.81 | MAT2A (0.67) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |