Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 18/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24596333 | 1.00 | MAT2A (0.48) | MAT2ARXFP1TRPA1 | |
| SCHEMBL29789966 | 0.93 | MAT2A (0.51) | MAT2ARXFP1 | |
| SCHEMBL24596150 | 0.93 | MAT2A (0.51) | MAT2ARXFP1 | |
| SCHEMBL24596242 | 0.91 | MAT2A (0.50) | MAT2ARXFP1 | |
| SCHEMBL29789901 | 0.91 | MAT2A (0.50) | MAT2ARXFP1 | |
| SCHEMBL24596152 | 0.90 | MAT2A (0.47) | MAT2ARXFP1 | |
| SCHEMBL29789921 | 0.90 | MAT2A (0.47) | MAT2ARXFP1 | |
| SCHEMBL29789945 | 0.88 | MAT2A (0.46) | MAT2ARXFP1 | |
| SCHEMBL24596216 | 0.88 | MAT2A (0.46) | MAT2ARXFP1 | |
| SCHEMBL24596170 | 0.85 | MAT2A (0.50) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |