Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | PREP | P48147 | 4/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727022 | 1.00 | CA12 (0.41) | CA12CA1CA9PREPCHRNB2 | |
| SCHEMBL30277881 | 0.81 | PREP (0.43) | CA12CA1CA9PREPCHRNB2 | |
| SCHEMBL2641955 | 0.81 | PREP (0.43) | CA12CA1CA9PREPCHRNB2 | |
| SCHEMBL30152184 | 0.80 | CHRNB2 (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL18990452 | 0.80 | CHRNB2 (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL6855170 | 0.79 | CA12 (0.41) | CA12CA1CA9PREPALOX5AP | |
| SCHEMBL13534994 | 0.79 | CA12 (0.41) | CA12CA1CA9PREPALOX5AP | |
| SCHEMBL29875070 | 0.79 | ALOX5AP (0.43) | CA12CA1CA9PREPALOX5AP | |
| SCHEMBL22581908 | 0.79 | CA12 (0.41) | CA12CA1CA9PREPALOX5AP | |
| SCHEMBL19924498 | 0.79 | ALOX5AP (0.43) | CA12CA1CA9PREPALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4038066-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2022-08-10 | — | — | EP | disclosed |
| CN-114787159-A | BRM targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-07-22 | — | — | CN | disclosed |