Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2282489 | 1.00 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL2168623 | 1.00 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL2282582 | 1.00 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL15930057 | 0.91 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL2167750 | 0.91 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL6255431 | 0.88 | TNF (0.53) | MEN1KMT2AALDH1A1KDM4ETNF | |
| SCHEMBL6268629 | 0.86 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL2168112 | 0.86 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL2288486 | 0.86 | ATM (0.46) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL2278593 | 0.84 | TNF (0.47) | MEN1KMT2AALDH1A1MAPK1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907314-A | Chemical synthesis method of pomalidomide | 浙江工业大学 | 2022-08-16 | — | — | CN | disclosed |